SPAdes: de novo genome assembly Formula was removed
Last versions were
spades requires the following formula to be installed:
cmake 3.10.3 Cross-platform make

Reverse dependencies

The following formulae require spades to be installed:
rampart 0.12.2 Configurable de novo assembly pipeline
unicycler 0.4.3 Hybrid assembly pipeline for bacterial genomes
circlator 1.5.3 Tool to circularize genome assemblies

Recent formula history

Shaun Jackman spades: migrate to homebrew/core (#6504)
Shaun Jackman spades 3.11.0
ilovezfs spades: revision for gcc
ilovezfs spades 3.10.1
ilovezfs spades: put back the Linux bottle

Formula code at GitHub